Skip to content
Evidence profile · Longevity
§Evidence profile · Longevity

GHK-Cu

A naturally occurring copper-binding tripeptide with dermal-remodeling research.

Evidence grade: Moderate

What GHK-Cu is

GHK-Cu is a well-characterized copper peptide with a substantial literature in skin remodeling and gene-expression modulation, much of it topical rather than injectable.

Mechanism (preclinical)

Delivers copper and modulates expression of genes tied to tissue remodeling and antioxidant response.

Primary research areas

Skin remodelingCollagen synthesisGene-expression modulation

Selected studies

  • Gene-expression profiling

    2012

    Broad modulation toward tissue-repair programs.

Regulatory status

Cosmetic topical uses exist; injectable use is research-only and not FDA-approved.

If you source GHK-Cu for laboratory research

Buy only from a vendor that publishes a lot-matched COA from an independent laboratory. Check the lot number on the vial against the certificate. Read the HPLC result and the mass spectrometry result. Ask for the chromatogram.